Regenerative Medicine Access · Powered by Platinum Biologics

The Future of Medicine
Is Already Here.

Stem Cells · Exosomes · Wharton’s Jelly — now in your practice,
legally and with confidence.

ISO Certified Largest IRB for Biologics GMP Compliant Cash-Pay Model AATB Guidelines
$22K+
Avg. Net Revenue Increase
8
Premium Product Lines
180B
Exosomes/mL (Nano Xsomes)
10 min
All We Ask For

Biologics knowledge hub

Everything you need to understand
regenerative medicine.

From stem cells to exosomes, PRP to Wharton’s Jelly — every biologic modality explained with peer-reviewed science, plain-language guides, and clinical evidence for patients and providers alike.

All biologic modalities covered
Wharton’s Jelly / MSCs
Exosomes / EVs
Platelet-Rich Plasma
Bone Marrow Aspirate
Adipose-Derived MSCs
Amniotic Membrane
Umbilical Cord Blood
Lyophilized Allografts
▸ 200+ peer-reviewed studies · Updated 2025
Largest IRB for biologics
ISO certified manufacturing
GMP compliant processes
AATB accredited
FDA registered · 21 CFR Part 1271
Section 361 HCT/P compliant
200+ peer-reviewed studies
12 clinical specialties covered

Every regenerative therapy, explained

Each modality covers mechanism of action, tissue sources, growth factor profiles, clinical applications, safety considerations, and regulatory status.

Wharton’s Jelly / WJ-MSCs
Umbilical cord-derived MSCs — highest MSC density of any perinatal tissue. Collagen I/III/V, long-chain hyaluronic acid, and 60+ growth factors including TGF-β, VEGF, and IL-1RA.
OrthopedicsNeurologyAesthetics
Exosomes & Extracellular Vesicles
Nano-scale lipid vesicles (30-150 nm) carrying miRNA, proteins, and growth factors. Acellular — no transplant risks. Shelf-stable when lyophilized.
Anti-inflammatoryHair restorationWound healing
Platelet-Rich Plasma (PRP)
Autologous concentration of platelets and growth factors (VEGF, TGF-β1, PDGF-AA). Three preparation generations. Same-day processing from patient blood.
TendinopathyAlopeciaAesthetics
Bone Marrow Aspirate (BMAC)
MSCs, hematopoietic progenitors, and growth factors from the iliac crest. Supports ACL reconstruction, cartilage repair, and ligament healing.
ACL repairCartilageSpine
Adipose-Derived MSCs (ADSCs)
Harvested via lipoaspirate with abundant cell yield. Adipogenic, osteogenic, and chondrogenic differentiation. Strong immunosuppressive paracrine profile.
Wound healingJoint painAesthetics
Amniotic Membrane & Fluid
Rich in EGF, bFGF, collagen IV, and proteoglycans. Anti-adhesive, anti-inflammatory, immunomodulatory. Primary in ophthalmology, orthopaedics, wound care.
OphthalmologyWound careJoint pain
Umbilical Cord Blood
Hematopoietic stem cells (HSCs) with established use in hematologic disease. Emerging evidence in neurological and metabolic applications. Cryo-banked at birth.
HematologyNeurologyOncology
Lyophilized Allografts
Freeze-dried WJ, exosome, or amniotic products — shelf-stable at ambient temperature, no cold chain required. Preserves growth factor activity for point-of-care use.
Point of careNo cold chainWound care

Find biologics by what you’re treating

Each condition page maps available biologics to clinical evidence, typical protocols, and questions to ask your provider before treatment.

How biologics work — plain language

Understanding the mechanism helps you have better conversations with your provider and set realistic expectations.

01
Tissue sourcing & ethical donation
Allogeneic biologics come from ethically donated human tissue — umbilical cords, placenta, cord blood — collected from consenting donors at healthy full-term deliveries. All donors undergo serological screening per FDA and AATB protocols. Autologous products (PRP, BMAC) come from the patient’s own body.
02
cGMP processing & concentration
Tissue is processed in ISO Class cleanrooms to isolate MSCs, exosomes, or growth factor concentrates. Every step is lot-tracked per FDA guidelines. Lyophilization or cryopreservation at −80°C locks in biological activity for storage and overnight shipping.
03
Third-party sterility testing
Every lot is quarantined until independent sterility, potency, and identity testing is completed by a third-party laboratory. Certificates of analysis are traceable to the specific lot administered to each patient. No exceptions.
04
Delivery to the treatment site
Products are injected intra-articularly (joints), intradermally (skin/scalp), or via IV depending on the biologic type and indication. Shelf-stable lyophilized products ship overnight at room temperature; frozen products ship on dry ice, arriving by 10:30 AM next business day.
05
Paracrine signaling & cellular repair
Growth factors and exosomes communicate with local cells via paracrine signaling — modulating inflammation (IL-1RA, TGF-β), promoting angiogenesis (VEGF), and stimulating native progenitor cells to repair damaged tissue. Most biologics act through these indirect mechanisms rather than direct cell engraftment.
06
Tissue regeneration over time
Wound healing may show response within days. Musculoskeletal applications typically require a 4-12 week observation window. Hair restoration protocols require 3-6 months before visible results. Outcomes vary by patient, condition severity, and product quality.
Key growth factors in WJ-MSC products
TGF-β1
Very high
VEGF
Very high
PDGF-AA
High
IL-1RA
Moderate
IGFBPs
Moderate
EGF
Present
HGF
Present
PGF
Present

Source: Drobiova et al., Frontiers in Cell & Developmental Biology, 2023

MSC yield by tissue source
Wharton’s Jelly✓ Highest
Adipose tissueHigh / autologous
Bone marrowModerate · invasive
PlacentaModerate
Amniotic fluidLow-moderate
Peripheral bloodVery low

How each biologic stacks up

High-level comparison across clinical, logistical, and regulatory dimensions.

ModalitySourceAutologousMSCs presentExosomes / EVsStoragePrimary indications
Wharton’s Jelly (WJ-MSCs)Umbilical cord Highest yield−80°C or lyophilizedOrthopedic, neuro, aesthetics
Exosomes (lyophilized)MSC-conditioned media PrimaryAmbient, shelf-stable 2 yrHair, aesthetics, inflammation
PRPPatient’s own bloodSame-day use onlyTendinopathy, aesthetics, hair
Bone Marrow Aspirate (BMAC)Iliac crestSame-day use onlyACL, cartilage, ligament
Adipose-Derived MSCsLipoaspirate (fat)Processed same dayWound healing, joint, aesthetics
Amniotic membranePlacenta / amnionSparseFrozen or lyophilizedOphthalmology, wound, joint
Umbilical cord bloodCord bloodLowCryo-bankedHematologic disease, neuro
Lyophilized allograftsWJ / amniotic / exosomeRoom temp 1-2+ yearsAll · point-of-care friendly

Peer-reviewed studies, organized for you

Curated from PubMed, PMC, and ClinicalTrials.gov — filtered by modality, condition, and study type.

Review
Biologic therapies in sports-related tendon and ligament injuries: mechanisms, clinical efficacy, and limitations
PMC · 2025 · PRP & MSCs in tendinopathy and ACL reconstruction
Meta-analysis
Exosome therapy, PRP, and minoxidil for androgenetic alopecia: a systematic review comparing three modalities
Cureus · July 2025 · Darwish et al.
Review
Wharton’s Jelly MSC secretome: clinical applications in immunomodulation, tissue repair, and anti-fibrotic effects
Frontiers in Cell & Developmental Biology · 2023 · Drobiova et al.
Clinical trial
Mechanically engineered UCMSC-derived exosomes vs. conventional exosomes and PRP for endometrial injury repair
ClinicalTrials.gov · NCT06896747 · Active enrolling
Review
PRP-derived exosomes accelerate healing of diabetic foot ulcers through macrophage M2 polarization
Clinical & Experimental Medicine · May 2025
Review
Biologics for bone and soft tissue regeneration: PRP, BMAC, adipose, amniotic, Wharton’s Jelly, and cord blood
Biomedicines (MDPI) · 2024 · Multi-modality clinical review
Review
Regenerative therapies for androgenetic alopecia: PRP, photobiomodulation, stem cells, and exosomes
Medical Sciences (MDPI) · 2025 · Gupta, Wang et al.
Meta-analysis
Biologic augmentation in ACL reconstruction: PRP and BMAC — tunnel widening, fibrocartilage, and mechanical strength
PMC · 2025 · Sports surgery biologics
Review
Characteristics and clinical applications of Wharton’s Jelly-derived MSCs: neurological, hepatic, orthopedic applications
ScienceDirect · 2019 · Foundational WJ-MSC review
View full research library (200+ studies) ▸

Videos, podcasts & infographics

Animated mechanism explainers, clinician interviews, patient outcome stories, and downloadable infographics.

Browse full media library ▸

The terminology, demystified

60+ terms from MSC to miRNA, paracrine to HCT/P — defined in plain English with clinical context.

Mesenchymal stem cell (MSC)
Multipotent stromal cell capable of differentiating into bone, cartilage, fat, and muscle. The primary cellular driver of biologic tissue repair.
Exosome
Nano-sized extracellular vesicle (30-150 nm) secreted by cells. Carries miRNA, proteins, and lipids that regulate neighboring cell behavior.
Paracrine signaling
Cell communication via secreted molecules that act on nearby cells. The primary mechanism of MSC-based biologics — no cell migration required.
Growth factor
Signaling protein that stimulates cell proliferation, differentiation, or survival. Key examples: VEGF, TGF-β, PDGF-AA, IL-1RA, IGF-1.
HCT/P · 21 CFR Part 1271
Human cells, tissues, and cellular/tissue-based products regulated by the FDA. Section 361 products are minimally manipulated and homologous-use.
Lyophilization
Freeze-drying process that removes water through sublimation. Extends shelf life to 2+ years at room temperature while preserving growth factor activity.
Autologous vs. allogeneic
Autologous = from the patient’s own body (PRP, BMAC). Allogeneic = from a donor (WJ-MSCs, amniotic, cord blood).
IRB
Independent ethics committee reviewing clinical applications for safety, ethics, and informed consent. Our Biologics carries the largest IRB for biologics in the industry.
Wharton’s Jelly
Gelatinous connective tissue of the umbilical cord. Contains the highest MSC concentration of any tissue source, plus collagen I/III/V and 60+ growth factors.
View full glossary (60+ terms) ▸

Questions patients actually ask

Most regenerative biologics are regulated as HCT/Ps under FDA 21 CFR Part 1271, Section 361. They are registered, screened, and traceable products, but are not individually “FDA-approved” for specific indications the way drug products are. All legitimate products must be manufactured in FDA-registered, cGMP-compliant, AATB-accredited facilities.
Stem cells (MSCs) are living cells that communicate with surrounding tissue and modulate the immune system. Exosomes are acellular vesicles — nano-packages released by stem cells containing the signaling molecules responsible for most therapeutic effect. Exosome products carry no live cells, making them shelf-stable and free of cell-transplant risks.
WJ-MSCs have higher proliferative potential, a faster growth rate, and retain multipotency for more passages in vitro than adult-derived MSCs. Perinatal tissue carries lower immunogenicity due to low HLA expression. The WJ matrix itself contributes structural collagen, hyaluronic acid, and proteoglycans — each with independent therapeutic value.
Most regenerative biologic applications are currently cash-pay. Some policies cover autologous PRP in specific orthopedic contexts. Allogeneic products are rarely reimbursed as of 2025. Coverage is evolving as clinical evidence matures.
Biologics are not cures and outcomes vary significantly by patient, condition severity, product quality, and administration technique. Musculoskeletal applications typically show a 4-12 week response window. Hair restoration requires 3-6 months. A reputable provider will discuss realistic expectations before any treatment.
An Institutional Review Board reviews the safety, ethics, and informed consent protocols for clinical applications. For regenerative biologics — operating outside the traditional FDA drug approval pathway — IRB oversight provides patients with documented independent review. Our Biologics carries the largest IRB for biologics in the industry.
⚖️
Largest IRB in Biologics · Section 361 HCT/P · AATB Accredited
Important Regulatory Notice

The regenerative biologics offered through Our Biologics Distributors and manufactured by Platinum Biologics are human cellular and tissue-based products (HCT/Ps) regulated under FDA 21 CFR Part 1271, Section 361 — not FDA-approved drug products.

These products have not been evaluated by the FDA for safety or efficacy for any specific indication. They are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. This material is intended for licensed healthcare professionals only.

Already using biologics?
We guarantee ours are better — and we’ll buy out your current inventory to prove it.

Our Biologics Distributors connects clinicians directly to the most advanced regenerative products available — sourced from Platinum Biologics, an Orlando-based, ISO-certified, FDA-registered, GMP-compliant manufacturer.

We help practices escape the cycle of declining insurance reimbursements by creating a high-margin, cash-pay revenue stream grounded in real science and patient outcomes.

Give us 10 minutes. We’ll show you what $22,000+ in additional annual revenue looks like for your practice — completely on us.

Eight Precision
Regenerative Products

Every product is manufactured in cGMP ISO Class cleanrooms, lot-tracked, and third-party sterility tested before it reaches your clinic.

Nano Flex
Wharton’s Jelly 150mg or 300mg. MSC matrix, collagen I/III/V, hyaluronic acid.
From $561
Nano Flow
40M MSC growth factors — highest VEGF & PGF of any allograft on the market.
From $711
Nano AER
50B lyophilized exosomes. Shelf-stable, no refrigeration required.
$500
Nano AER Plus
90B lyophilized exosomes — elevated potency for advanced cases.
$750
Nano DPM
First lyophilized Wharton’s Jelly at 95mg. No cryogenic storage needed.
$300
Nano EX
30B exosomes — 60+ growth factors incl. IL-1RA, TGF-β, VEGF.
$250
Nano Xsomes
180 Billion exosomes/mL — ultra-high concentration injectable.
$1,250
Nano PRP Jelly
3ml / 70mg Wharton’s Jelly — ideal for PRP combination protocols.
$150

Five Reasons Practices
Switch to Us

01

$22,000 Avg. Net Revenue Increase

Supplement the ever-decreasing insurance reimbursement model with a high-margin cash-pay revenue stream that your patients are actively seeking.

02

We’ll Buy Out Your Current Inventory

Already using biologics? We guarantee ours are better and will purchase your current supply and replace it with a clinically superior product.

03

Doctors On Call for Your Support

Dedicated physician support for protocols, dosing, and problem solving. We make your team look like experts overnight.

04

Amazing Patient Outcomes

Better clinical results lead to stronger reviews, more referrals, and a reputation that compounds over time in your community.

05

Ask What We Can Do — On Us

We want one opportunity to show you what’s possible. Let us help your office look better and feel better — completely on us.

IRB Protection — Our Differentiator

We carry the largest IRB for biologics in the industry, providing you and your patients with an added layer of compliance, documentation, and confidence.

From Healthy Donors
To Your Clinic

Every product has a complete, traceable chain of custody from ethical donation to overnight delivery.

STEP 01
Screened Donors
Consenting mothers at healthy full-term deliveries. Serology and social history reviewed by Medical Director before acceptance.
STEP 02
Tissue Collection
Wharton’s Jelly harvested at C-section by licensed professionals in a sterile environment within 48 hours of delivery.
STEP 03
cGMP Processing
ISO Class cleanrooms. Cleaned, decontaminated, and lot-tracked per FDA & AATB guidelines throughout every stage.
STEP 04
Preservation
Slow-rate freezing at -80°C or lyophilization — biological activity is fully preserved throughout the process.
STEP 05
Third-Party Testing
Every lot is quarantined until independent sterility testing is completed and passed. No exceptions.
STEP 06
Overnight Delivery
Shipped on dry ice in validated containers. Delivered to your clinic by 10:30 AM next business day.

Why Wharton’s Jelly
Outperforms Everything

Derived from umbilical cord Wharton’s Jelly donated by consenting mothers at healthy full-term deliveries — the highest MSC concentration of any tissue source.

  • Highest MSC Concentration
    More stem cells per mL than bone marrow, adipose tissue, or placenta.
  • 60+ Growth Factors
    TGF-β, VEGF, PDGF-AA, IL-1RA, IGFBPs — full spectrum for tissue repair.
  • Collagen Types I, III & V
    Natural scaffold for cellular adhesion and tissue regeneration.
  • Long-Chain Hyaluronic Acid
    Deep joint lubrication and sustained tissue hydration.
  • Exosomes & EVs
    Reduce inflammation and drive cellular healing via paracrine signaling.
  • Immune Privileged Tissue
    Low immune response risk — a safer, more consistent choice for your patients.
  • Chondroitin & Proteoglycans
    Structural support for cartilage and connective tissue repair.

Platinum Biologics
Sets the Standard

Orlando, FL · FDA Registered · AATB Accredited

ISO
Certified
GMP
Compliant
AATB
Guidelines
IRB
Largest in Biologics

Ordering Information

  • ▸ Submit orders by 3:00 PM ET for same-day shipment
  • ▸ Shipments Monday – Thursday only
  • ▸ Dry ice shipping: $150 · Shelf-stable shipping: $50
  • ▸ Direct: [email protected]
  • ▸ Manufacturer support: 866.755.2334

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Your Representative
Matt Griffin
Sales Representative · Our Biologics Distributors
Contact
972.550.0000
Website / Resources
ourbiologics.com
IRB Docs · Research Library · Product Guides
⚖️
Largest IRB in Biologics · Section 361 HCT/P · AATB Accredited

Important Regulatory Notice

The regenerative biologics offered through Our Biologics Distributors and manufactured by Platinum Biologics are human cellular and tissue-based products (HCT/Ps) regulated under FDA 21 CFR Part 1271, Section 361 — not FDA-approved drug products. They are minimally manipulated, intended for homologous use, and comply with AATB accreditation standards.

All clinical applications are conducted under Institutional Review Board (IRB), providing the highest level of patient protection, ethical review, and informed consent protocols available outside of an FDA drug approval pathway.

These products have not been evaluated by the FDA for safety or efficacy for any specific indication. They are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Clinicians are responsible for independent evaluation of suitability for each patient. This material is intended for licensed healthcare professionals only and does not constitute medical advice.